Mass Spectral studies of steroidal thiazole
Azhar U. Khan1,2*, Nazia Malik1, Shaila Khan2, Iqbal2 and M. Mushfiq1
1Department of Chemistry Aligarh Muslim University, Aligarh-202002, India
2Al.Falah School of Engineering and Technology Dhauj Faridabad (Haryana)
Mass spectra of some steroidal thiazole as an attempt to establish spectra structure relationship. The compounds included in the study are 2’-N-phenylamino-5α-cholest-6-eno[6,7-d] thiazole (1) 3β-acetoxy-2’-N-phenylamino-5α-cholest-6-eno[6,7-d] thiazole and 3β-propanoyloxy 2’-phenylamino-5α-cholest 6-eno[6,7-d] thiazole. These compounds are structurally very close to each other. It was anticipated that they will follow similar fragmentation patterns thus offering a simple and effective method of their characterization by mass spectrometer. The mass spectrum of above compound (1) gave a prominent molecular peak at mz 58 (C34H50N2S).
Keywords: Steroidal Ketones, Thiazole Steroidal Thiazole And Mass Fragmentation